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Cigarette Smoking and p16(INK4α) Gene Promoter Hypermethylation in Non-Small Cell Lung Carcinoma Patients: A Meta-Analysis

BACKGROUND: Aberrant methylation of promoter DNA and transcriptional repression of specific tumor suppressor genes play an important role in carcinogenesis. Recently, many studies have investigated the association between cigarette smoking and p16(INK4α) gene hypermethylation in lung cancer, but cou...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhu, Wei, Yang, Ping, Liu, Tao, Jiang, Mei, He, Zhi-Ni, Zhang, Shi-Xin, Chen, Wei-Qing, Chen, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236763/
https://www.ncbi.nlm.nih.gov/pubmed/22174919
http://dx.doi.org/10.1371/journal.pone.0028882