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Cigarette Smoking and p16(INK4α) Gene Promoter Hypermethylation in Non-Small Cell Lung Carcinoma Patients: A Meta-Analysis
BACKGROUND: Aberrant methylation of promoter DNA and transcriptional repression of specific tumor suppressor genes play an important role in carcinogenesis. Recently, many studies have investigated the association between cigarette smoking and p16(INK4α) gene hypermethylation in lung cancer, but cou...
Autores principales: | Zhang, Bo, Zhu, Wei, Yang, Ping, Liu, Tao, Jiang, Mei, He, Zhi-Ni, Zhang, Shi-Xin, Chen, Wei-Qing, Chen, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236763/ https://www.ncbi.nlm.nih.gov/pubmed/22174919 http://dx.doi.org/10.1371/journal.pone.0028882 |
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