Mutations Altering the Interplay between GkDnaC Helicase and DNA Reveal an Insight into Helicase Unwinding

Replicative helicases are essential molecular machines that utilize energy derived from NTP hydrolysis to move along nucleic acids and to unwind double-stranded DNA (dsDNA). Our earlier crystal structure of the hexameric helicase from Geobacillus kaustophilus HTA426 (GkDnaC) in complex with single-s...

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Detalles Bibliográficos
Autores principales: Lo, Yu-Hua, Liu, Shih-Wei, Sun, Yuh-Ju, Li, Hung-Wen, Hsiao, Chwan-Deng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236778/
https://www.ncbi.nlm.nih.gov/pubmed/22174946
http://dx.doi.org/10.1371/journal.pone.0029016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236778/
https://www.ncbi.nlm.nih.gov/pubmed/22174946
http://dx.doi.org/10.1371/journal.pone.0029016

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