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Accuracy in Copy Number Calling by qPCR and PRT: A Matter of DNA
The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the performance of the two major techniques, quantitative PCR (qPCR) and paralog rati...
Autores principales: | Fernandez-Jimenez, Nora, Castellanos-Rubio, Ainara, Plaza-Izurieta, Leticia, Gutierrez, Galder, Irastorza, Iñaki, Castaño, Luis, Vitoria, Juan Carlos, Bilbao, Jose Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236783/ https://www.ncbi.nlm.nih.gov/pubmed/22174923 http://dx.doi.org/10.1371/journal.pone.0028910 |
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