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High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial
BACKGROUND AND PURPOSE: High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies. METHODS: In a randomized, double-blind placebo-controlled trial in 12 patients undergoing...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237031/ https://www.ncbi.nlm.nih.gov/pubmed/21751861 http://dx.doi.org/10.3109/17453674.2011.596063 |
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author | Andersen, Lasse Ø Otte, Kristian S Husted, Henrik Gaarn-Larsen, Lissi Kristensen, Billy Kehlet, Henrik |
author_facet | Andersen, Lasse Ø Otte, Kristian S Husted, Henrik Gaarn-Larsen, Lissi Kristensen, Billy Kehlet, Henrik |
author_sort | Andersen, Lasse Ø |
collection | PubMed |
description | BACKGROUND AND PURPOSE: High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies. METHODS: In a randomized, double-blind placebo-controlled trial in 12 patients undergoing bilateral total hip arthroplasty (THA) in a fast-track setting, saline or high-volume (170 mL) ropivacaine (0.2%) with epinephrine (1:100,000) was administered to the wound intraoperatively along with supplementary postoperative injections via an intraarticular epidural catheter. Oral analgesia was instituted preoperatively with a multimodal regimen (gabapentin, celecoxib, and acetaminophen). Pain was assessed repeatedly for 48 hours postoperatively, at rest and with 45° hip flexion. RESULTS: Pain scores were low and similar between ropivacaine and saline administration. Median hospital stay was 4 (range 2–7) days. INTERPRETATION: Intraoperative high-volume infiltration with 0.2% ropivacaine with repeated intraarticular injections postoperatively may not give a clinically relevant analgesic effect in THA when combined with a multimodal oral analgesic regimen with gabapentin, celecoxib, and acetaminophen. |
format | Online Article Text |
id | pubmed-3237031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Informa Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-32370312012-01-03 High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial Andersen, Lasse Ø Otte, Kristian S Husted, Henrik Gaarn-Larsen, Lissi Kristensen, Billy Kehlet, Henrik Acta Orthop Article BACKGROUND AND PURPOSE: High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies. METHODS: In a randomized, double-blind placebo-controlled trial in 12 patients undergoing bilateral total hip arthroplasty (THA) in a fast-track setting, saline or high-volume (170 mL) ropivacaine (0.2%) with epinephrine (1:100,000) was administered to the wound intraoperatively along with supplementary postoperative injections via an intraarticular epidural catheter. Oral analgesia was instituted preoperatively with a multimodal regimen (gabapentin, celecoxib, and acetaminophen). Pain was assessed repeatedly for 48 hours postoperatively, at rest and with 45° hip flexion. RESULTS: Pain scores were low and similar between ropivacaine and saline administration. Median hospital stay was 4 (range 2–7) days. INTERPRETATION: Intraoperative high-volume infiltration with 0.2% ropivacaine with repeated intraarticular injections postoperatively may not give a clinically relevant analgesic effect in THA when combined with a multimodal oral analgesic regimen with gabapentin, celecoxib, and acetaminophen. Informa Healthcare 2011-08 2011-09-02 /pmc/articles/PMC3237031/ /pubmed/21751861 http://dx.doi.org/10.3109/17453674.2011.596063 Text en Copyright: © Nordic Orthopaedic Federation http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. |
spellingShingle | Article Andersen, Lasse Ø Otte, Kristian S Husted, Henrik Gaarn-Larsen, Lissi Kristensen, Billy Kehlet, Henrik High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title | High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title_full | High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title_fullStr | High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title_full_unstemmed | High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title_short | High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial |
title_sort | high-volume infiltration analgesia in bilateral hip arthroplasty: a randomized, double-blind placebo-controlled trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237031/ https://www.ncbi.nlm.nih.gov/pubmed/21751861 http://dx.doi.org/10.3109/17453674.2011.596063 |
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