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Pathophysiological insights in sickle cell disease

The first coherent pathophysiological scheme for sickle cell disease (SCD) emerged in the sixties-seventies based on an extremely detailed description of the molecular mechanism by which HbS in its deoxy-form polymerises and forms long fibres within the red blood cell that deform it and make it frag...

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Detalles Bibliográficos
Autores principales: Odièvre, Marie-Hélène, Verger, Emmanuelle, Silva-Pinto, Ana Cristina, Elion, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237253/
https://www.ncbi.nlm.nih.gov/pubmed/22089617