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Isothiocyanates Reduce Mercury Accumulation via an Nrf2-Dependent Mechanism during Exposure of Mice to Methylmercury

Background: Methylmercury (MeHg) exhibits neurotoxicity through accumulation in the brain. The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) plays an important role in reducing the cellular accumulation of MeHg. Objectives: We investigated the protective effect of isothiocy...

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Detalles Bibliográficos
Autores principales:	Toyama, Takashi, Shinkai, Yasuhiro, Yasutake, Akira, Uchida, Koji, Yamamoto, Masayuki, Kumagai, Yoshito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237354/ https://www.ncbi.nlm.nih.gov/pubmed/21382770 http://dx.doi.org/10.1289/ehp.1003123

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