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Identification of Candidate Genes Downstream of TLR4 Signaling after Ozone Exposure in Mice: A Role for Heat-Shock Protein 70

Background: Toll-like receptor 4 (TLR4) is involved in ozone (O(3))-induced pulmonary hyperpermeability and inflammation, although the downstream signaling events are unknown. Objectives: The aims of our study were to determine the mechanism through which TLR4 modulates O(3)-induced pulmonary respon...

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Detalles Bibliográficos
Autores principales: Bauer, Alison K., Rondini, Elizabeth A., Hummel, Kristin A., Degraff, Laura M., Walker, Christopher, Jedlicka, Anne E., Kleeberger, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237361/
https://www.ncbi.nlm.nih.gov/pubmed/21543283
http://dx.doi.org/10.1289/ehp.1003326