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Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae
The de novo biosynthetic machinery for both sphingolipid and ergosterol production in yeast is localized in the endoplasmic reticulum (ER) and Golgi. The interconnections between the two pathways are still poorly understood, but they may be connected in specialized membrane domains, and specific kno...
Autores principales: | Alvarez-Vasquez, Fernando, Riezman, Howard, Hannun, Yusuf A., Voit, Eberhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237449/ https://www.ncbi.nlm.nih.gov/pubmed/22194828 http://dx.doi.org/10.1371/journal.pone.0028344 |
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