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PEGylation Potentiates the Effectiveness of an Antagonistic Peptide That Targets the EphB4 Receptor with Nanomolar Affinity
The EphB4 receptor tyrosine kinase together with its preferred ligand, ephrin-B2, regulates a variety of physiological and pathological processes, including tumor progression, pathological forms of angiogenesis, cardiomyocyte differentiation and bone remodeling. We previously reported the identifica...
Autores principales: | Noberini, Roberta, Mitra, Sayantan, Salvucci, Ombretta, Valencia, Fatima, Duggineni, Srinivas, Prigozhina, Natalie, Wei, Ke, Tosato, Giovanna, Huang, Ziwei, Pasquale, Elena B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237458/ https://www.ncbi.nlm.nih.gov/pubmed/22194865 http://dx.doi.org/10.1371/journal.pone.0028611 |
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