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Cardiac Alpha-Myosin (MYH6) Is the Predominant Sarcomeric Disease Gene for Familial Atrial Septal Defects

Secundum-type atrial septal defects (ASDII) account for approximately 10% of all congenital heart defects (CHD) and are associated with a familial risk. Mutations in transcription factors represent a genetic source for ASDII. Yet, little is known about the role of mutations in sarcomeric genes in AS...

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Detalles Bibliográficos
Autores principales:	Posch, Maximilian G., Waldmuller, Stephan, Müller, Melanie, Scheffold, Thomas, Fournier, David, Andrade-Navarro, Miguel A., De Geeter, Bernard, Guillaumont, Sophie, Dauphin, Claire, Yousseff, Dany, Schmitt, Katharina R., Perrot, Andreas, Berger, Felix, Hetzer, Roland, Bouvagnet, Patrice, Özcelik, Cemil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237499/ https://www.ncbi.nlm.nih.gov/pubmed/22194935 http://dx.doi.org/10.1371/journal.pone.0028872

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