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Androgen Regulation of 5α-Reductase Isoenzymes in Prostate Cancer: Implications for Prostate Cancer Prevention

The enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT), performs key functions in the androgen receptor (AR) signaling pathway. The three isoenzymes of 5α-reductase identified to date are encoded by different genes: SRD5A1, SRD5A2, and SRD5A3. In this study, we investigate...

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Detalles Bibliográficos
Autores principales:	Li, Jin, Ding, Zhiyong, Wang, Zhengxin, Lu, Jing-Fang, Maity, Sankar N., Navone, Nora M., Logothetis, Christopher J., Mills, Gordon B., Kim, Jeri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237548/ https://www.ncbi.nlm.nih.gov/pubmed/22194926 http://dx.doi.org/10.1371/journal.pone.0028840

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