Cargando…

Pivotal Role of Toll-Like Receptors 2 and 4, Its Adaptor Molecule MyD88, and Inflammasome Complex in Experimental Tubule-Interstitial Nephritis

Tubule-interstitial nephritis (TIN) results in decreased renal function and interstitial inflammation, which ultimately leads to fibrosis. Excessive adenine intake can cause TIN because xanthine dehydrogenase (XDH) can convert this purine into an insoluble compound, which precipitates in the tubuli....

Descripción completa

Detalles Bibliográficos
Autores principales:	Correa-Costa, Matheus, Braga, Tarcio Teodoro, Semedo, Patricia, Hayashida, Caroline Yuri, Bechara, Luiz Roberto Grassmann, Elias, Rosa Maria, Barreto, Claudiene Rodrigues, Silva-Cunha, Claudia, Hyane, Meire Ioshie, Gonçalves, Giselle Martins, Brum, Patricia Chakur, Fujihara, Clarice, Zatz, Roberto, Pacheco-Silva, Alvaro, Zamboni, Dario S., Camara, Niels Olsen Saraiva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237574/ https://www.ncbi.nlm.nih.gov/pubmed/22194975 http://dx.doi.org/10.1371/journal.pone.0029004

Ejemplares similares

Oxidative Stress and Modification of Renal Vascular Permeability Are Associated with Acute Kidney Injury during P. berghei ANKA Infection
por: Elias, Rosa Maria, et al.
Publicado: (2012)

TLR2, TLR4 and the MYD88 Signaling Pathway Are Crucial for Neutrophil Migration in Acute Kidney Injury Induced by Sepsis
por: Castoldi, Angela, et al.
Publicado: (2012)

Increased Clearance of Reactive Aldehydes and Damaged Proteins in Hypertension-Induced Compensated Cardiac Hypertrophy: Impact of Exercise Training
por: Campos, Juliane Cruz, et al.
Publicado: (2015)

The dual effect of acetate on microglial TNF-α production
por: Fragas, Matheus Garcia, et al.
Publicado: (2022)

Lactate Up-Regulates the Expression of Lactate Oxidation Complex-Related Genes in Left Ventricular Cardiac Tissue of Rats
por: Gabriel-Costa, Daniele, et al.
Publicado: (2015)

Chronic VEGF Blockade Worsens Glomerular Injury in the Remnant Kidney Model
por: Machado, Flavia G., et al.
Publicado: (2012)

Adipose Tissue-Derived Stem Cells Reduce Acute and Chronic Kidney Damage in Mice
por: Burgos-Silva, Marina, et al.
Publicado: (2015)

Long-Term Aerobic Exercise Protects against Cisplatin-Induced Nephrotoxicity by Modulating the Expression of IL-6 and HO-1
por: Miyagi, Mariana Yasue Saito, et al.
Publicado: (2014)

The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis
por: Wong, Deysi V. T., et al.
Publicado: (2015)

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88
por: Castoldi, Angela, et al.
Publicado: (2017)

Combined Effect of AMPK/PPAR Agonists and Exercise Training in mdx Mice Functional Performance
por: Bueno Júnior, Carlos R., et al.
Publicado: (2012)

Macrophage Trafficking as Key Mediator of Adenine-Induced Kidney Injury
por: Correa-Costa, Matheus, et al.
Publicado: (2014)

Transcriptome Analysis of Renal Ischemia/Reperfusion Injury and Its Modulation by Ischemic Pre-Conditioning or Hemin Treatment
por: Correa-Costa, Matheus, et al.
Publicado: (2012)

TRAM Is Involved in IL-18 Signaling and Functions as a Sorting Adaptor for MyD88
por: Ohnishi, Hidenori, et al.
Publicado: (2012)

Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma
por: Trucco, Lucas Daniel, et al.
Publicado: (2017)

Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals
por: Yao, Xia-Ping, et al.
Publicado: (2023)

Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
por: Braga, Tarcio Teodoro, et al.
Publicado: (2016)

TACI triggers immunoglobulin class switching by activating B cells through the adaptor protein MyD88
por: He, Bing, et al.
Publicado: (2010)

Overexpression of the Toll-Like Receptor (TLR) Signaling Adaptor MYD88, but Lack of Genetic Mutation, in Myelodysplastic Syndromes
por: Dimicoli, Sophie, et al.
Publicado: (2013)

MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice
por: Layoun, Antonio, et al.
Publicado: (2018)

PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses
por: Palaniyandi, Suresh Selvaraj, et al.
Publicado: (2011)

Soluble Uric Acid Activates the NLRP3 Inflammasome
por: Braga, Tarcio Teodoro, et al.
Publicado: (2017)

DOCK8 functions as an adaptor that links Toll-like receptor–MyD88 signaling to B cell activation
por: Jabara, Haifa H., et al.
Publicado: (2012)

Role of MyD88-adaptor-like gene polymorphism rs8177374 in modulation of malaria severity in the Pakistani population
por: Rani, Asima, et al.
Publicado: (2017)

Plasmodium falciparum Malaria Susceptibility and Severity: Influence of MyD88-Adaptor-Like Gene (rs8177374) Polymorphism
por: Ammar, Amany I, et al.
Publicado: (2022)

A Regulatory miRNA–mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney Injury
por: de Almeida, Danilo Candido, et al.
Publicado: (2017)

The neuronal Shc adaptor in Alzheimer’s Disease
por: Triaca, Viviana, et al.
Publicado: (2018)

Protein Quality Control Disruption by PKCβII in Heart Failure; Rescue by the Selective PKCβII Inhibitor, βIIV5-3
por: Ferreira, Julio C. B., et al.
Publicado: (2012)

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease
por: Michaud, Jean-Philippe, et al.
Publicado: (2011)

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88
por: O’Carroll, Ailís, et al.
Publicado: (2018)

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation
por: Liu, Xing-Jun, et al.
Publicado: (2016)

Role of Adaptor Protein Myeloid Differentiation 88 (MyD88) in Post-Subarachnoid Hemorrhage Inflammation: A Systematic Review
por: Ahmed, Hammad, et al.
Publicado: (2021)

Respostas Fisiológicas à Caminhada Máxima e Submáxima em Pacientes com Doença Arterial Periférica Sintomática
por: Chehuen, Marcel, et al.
Publicado: (2021)

Induction of Heme Oxygenase-1 Can Halt and Even Reverse Renal Tubule-Interstitial Fibrosis
por: Correa-Costa, Matheus, et al.
Publicado: (2010)

A Yersinia ruckeri TIR Domain-Containing Protein (STIR-2) Mediates Immune Evasion by Targeting the MyD88 Adaptor
por: Liu, Tao, et al.
Publicado: (2019)

β(2)-Adrenergic Signaling Modulates Mitochondrial Function and Morphology in Skeletal Muscle in Response to Aerobic Exercise
por: Azevedo Voltarelli, Vanessa, et al.
Publicado: (2021)

Scallop IKK1 Responds to Bacterial and Virus-Related Pathogen Stimulation and Interacts With MyD88 Adaptor of Toll-Like Receptor Pathway Signaling
por: Li, Lingling, et al.
Publicado: (2022)

Regression of Albuminuria and Hypertension and Arrest of Severe Renal Injury by a Losartan-Hydrochlorothiazide Association in a Model of Very Advanced Nephropathy
por: Arias, Simone Costa Alarcon, et al.
Publicado: (2013)

Determinants of Health and Physical Activity Levels Among Breast Cancer Survivors During the COVID-19 Pandemic: A Cross-Sectional Study
por: Gurgel, Aline Rachel Bezerra, et al.
Publicado: (2021)

Corrigendum: Determinants of Health and Physical Activity Levels Among Breast Cancer Survivors During the COVID-19 Pandemic: A Cross-Sectional Study
por: Gurgel, Aline Rachel Bezerra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_45h4ojb2etad00hbdj49k8mdbv