Identification of Novel Androgen-Regulated Pathways and mRNA Isoforms through Genome-Wide Exon-Specific Profiling of the LNCaP Transcriptome

Androgens drive the onset and progression of prostate cancer (PCa) by modulating androgen receptor (AR) transcriptional activity. Although several microarray-based studies have identified androgen-regulated genes, here we identify in-parallel global androgen-dependent changes in both gene and altern...

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Detalles Bibliográficos
Autores principales: Rajan, Prabhakar, Dalgliesh, Caroline, Carling, Phillippa J., Buist, Thomas, Zhang, Chaolin, Grellscheid, Sushma N., Armstrong, Kelly, Stockley, Jacqueline, Simillion, Cedric, Gaughan, Luke, Kalna, Gabriela, Zhang, Michael Q., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237596/
https://www.ncbi.nlm.nih.gov/pubmed/22194994
http://dx.doi.org/10.1371/journal.pone.0029088

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