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Remodeling of Hepatic Metabolism and Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides

Glucagon is believed to be one of the most important peptides for upregulating blood glucose levels. However, homozygous glucagon–green fluorescent protein (gfp) knock-in mice (Gcg(gfp/gfp): GCGKO) are normoglycemic despite the absence of proglucagon-derived peptides, including glucagon. To characte...

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Detalles Bibliográficos
Autores principales: Watanabe, Chika, Seino, Yusuke, Miyahira, Hiroki, Yamamoto, Michiyo, Fukami, Ayako, Ozaki, Nobuaki, Takagishi, Yoshiko, Sato, Jun, Fukuwatari, Tsutomu, Shibata, Katsumi, Oiso, Yutaka, Murata, Yoshiharu, Hayashi, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237648/
https://www.ncbi.nlm.nih.gov/pubmed/22187375
http://dx.doi.org/10.2337/db11-0739