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Somatostatin Receptor Type 2 Antagonism Improves Glucagon and Corticosterone Counterregulatory Responses to Hypoglycemia in Streptozotocin-Induced Diabetic Rats

Diminished responsiveness to hypoglycemia contributes to defective counterregulation in diabetes. Pancreatic and/or circulating somatostatin are elevated in diabetes, which may inhibit counterregulatory hormone release during hypoglycemia. Thus, a selective somatostatin receptor type 2 antagonist (S...

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Detalles Bibliográficos
Autores principales:	Yue, Jessica T.Y., Burdett, Elena, Coy, David H., Giacca, Adria, Efendic, Suad, Vranic, Mladen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237655/ https://www.ncbi.nlm.nih.gov/pubmed/22106159 http://dx.doi.org/10.2337/db11-0690

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