Cargando…

Distinguishing Persistent Insulin Autoantibodies With Differential Risk: Nonradioactive Bivalent Proinsulin/Insulin Autoantibody Assay

A subset of children develops persistent insulin autoantibodies (IAA; almost always as the only islet autoantibody) without evidence of progression to diabetes. The aim of the current study was the development and characterization of the performance of a nonradioactive fluid phase IAA assay in relat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Liping, Miao, Dongmei, Scrimgeour, Laura, Johnson, Kelly, Rewers, Marian, Eisenbarth, George S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237666/ https://www.ncbi.nlm.nih.gov/pubmed/22124462 http://dx.doi.org/10.2337/db11-0670

Ejemplares similares

Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies
por: Zhao, Zhiyuan, et al.
Publicado: (2016)

Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity
por: Yu, Liping, et al.
Publicado: (2013)

Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young
por: Steck, Andrea K., et al.
Publicado: (2011)

GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes
por: Miao, Dongmei, et al.
Publicado: (2013)

Identification of Autoantibodies to a Hybrid Insulin Peptide in Type 1 Diabetes
por: Wenzlau, Janet M., et al.
Publicado: (2023)

Increased Effector Memory Insulin-Specific CD4(+) T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes
por: Spanier, Justin A., et al.
Publicado: (2017)

Preexisting Autoantibodies Predict Efficacy of Oral Insulin to Cure Autoimmune Diabetes in Combination With Anti-CD3
por: Mamchak, Alusha A., et al.
Publicado: (2012)

Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8(+) T Cells
por: Pearson, James A., et al.
Publicado: (2016)

A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes
por: Wenzlau, Janet M., et al.
Publicado: (2008)

Electrochemiluminescence Assays for Human Islet Autoantibodies
por: Gu, Yong, et al.
Publicado: (2018)

The utility of phospholipase A2 receptor autoantibody in membranous nephropathy after kidney transplantation
por: Xipell, Marc, et al.
Publicado: (2018)

High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes
por: Jia, Xiaofan, et al.
Publicado: (2021)

Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops
por: Marzinotto, Ilaria, et al.
Publicado: (2023)

Detection of Antibodies Directed to the N-Terminal Region of GAD Is Dependent on Assay Format and Contributes to Differences in the Specificity of GAD Autoantibody Assays for Type 1 Diabetes
por: Williams, Alistair J.K., et al.
Publicado: (2015)

Associations of age with serum insulin, proinsulin and the proinsulin-to-insulin ratio: a cross-sectional study
por: Bryhni, Bente, et al.
Publicado: (2010)

Improving clinical utility of GAD65 autoantibodies by electrochemiluminescence assay and clinical phenotype when identifying autoimmune adult-onset diabetes
por: Gu, Yong, et al.
Publicado: (2021)

Zinc transporter 8 autoantibody testing requires age-related cut-offs
por: Grace, Sian Louise, et al.
Publicado: (2021)

Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes
por: Acevedo-Calado, Maria J., et al.
Publicado: (2019)

Serum Insulin, Proinsulin and Proinsulin/Insulin Ratio in Type 2 Diabetic Patients: As an Index of β-Cell Function or Insulin Resistance
por: Kim, Nan Hee, et al.
Publicado: (2000)

Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals With Presymptomatic Type 1 Diabetes
por: Kwon, Bum Chul, et al.
Publicado: (2022)

Germline TRAV5D-4 T-Cell Receptor Sequence Targets a Primary Insulin Peptide of NOD Mice
por: Nakayama, Maki, et al.
Publicado: (2012)

Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice
por: Levisetti, Matteo G., et al.
Publicado: (2008)

THU267 A Novel In Vitro Assay Correlates Insulin Receptor Autoantibodies To Fasting Insulin In Type B Insulin Resistance
por: Abel, Brent, et al.
Publicado: (2023)

High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously
por: Gu, Yong, et al.
Publicado: (2019)

Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: A Twin and Population Study
por: Beyan, Huriya, et al.
Publicado: (2012)

The measurement of autoantibodies to insulin informs diagnosis of diabetes in a childhood population negative for other autoantibodies
por: Williams, Claire L., et al.
Publicado: (2022)

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
por: Silva, Diego G., et al.
Publicado: (2011)

Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis
por: Williams, MacKenzie D., et al.
Publicado: (2021)

Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome
por: Church, David, et al.
Publicado: (2018)

Methods in nonradioactive detection
Publicado: (1993)

Following the Fate of One Insulin-Reactive CD4 T cell: Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice
por: Fousteri, Georgia, et al.
Publicado: (2012)

Proinsulin-specific T regulatory cells may control immune responses in type 1 diabetes: implications for adoptive therapy
por: Gliwiński, Mateusz, et al.
Publicado: (2020)

The Autoantibody Array Assay: A Novel Autoantibody Detection Method
por: Norimatsu, Yuta, et al.
Publicado: (2023)

Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes
por: Fourlanos, Spiros, et al.
Publicado: (2011)

Surface Plasmon Resonance Reveals a Different Pattern of Proinsulin Autoantibodies Concentration and Affinity in Diabetic Patients
por: Trabucchi, Aldana, et al.
Publicado: (2012)

Islet Autoantibody Detection by Electrochemiluminescence (ECL) Assay
por: Gu, Yong, et al.
Publicado: (2017)

Increased Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B in Patients With Kidney Allograft Antibody-mediated Rejection
por: Clotet-Freixas, Sergi, et al.
Publicado: (2021)

Autoimmune Hypoglycemia in a Patient with Characterization of Insulin Receptor Autoantibodies
por: Chon, Suk, et al.
Publicado: (2011)

Autoantibodies to Insulin and Dysglycemia in People With and Without Diabetes: An Underdiagnosed Association
por: Pavithran, Praveen Valiyaparambil, et al.
Publicado: (2016)

Searching for the Culprit: When Diabetic Ketoacidosis Presents With Insulin Autoantibodies
por: Garcia-Avila, Scarlette, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dho606tssmsnmijvu2on2hbtiq