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Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice

Diabetes is a cause of cardiac dysfunction, reduced myocardial perfusion, and ultimately heart failure. Nerve growth factor (NGF) exerts protective effects on the cardiovascular system. This study investigated whether NGF gene transfer can prevent diabetic cardiomyopathy in mice. We worked with mice...

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Detalles Bibliográficos
Autores principales:	Meloni, Marco, Descamps, Betty, Caporali, Andrea, Zentilin, Lorena, Floris, Ilaria, Giacca, Mauro, Emanueli, Costanza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237667/ https://www.ncbi.nlm.nih.gov/pubmed/22187379 http://dx.doi.org/10.2337/db11-0763

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