A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5

Hepatic autonomic nerves regulate postprandial hepatic glucose uptake, but the signaling pathways remain unknown. We tested the hypothesis that serotonin (5-hydroxytryptamine [5-HT]) exerts stimulatory and inhibitory effects on hepatic glucose disposal. Ligands of diverse 5-HT receptors were used to...

Descripción completa

Detalles Bibliográficos
Autores principales: Tudhope, Susan J., Wang, Chung-Chi, Petrie, John L., Potts, Lloyd, Malcomson, Fiona, Kieswich, Julius, Yaqoob, Muhammad M., Arden, Catherine, Hampson, Laura J., Agius, Loranne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237670/
https://www.ncbi.nlm.nih.gov/pubmed/22106156
http://dx.doi.org/10.2337/db11-0870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237670/
https://www.ncbi.nlm.nih.gov/pubmed/22106156
http://dx.doi.org/10.2337/db11-0870

Ejemplares similares