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A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5

Hepatic autonomic nerves regulate postprandial hepatic glucose uptake, but the signaling pathways remain unknown. We tested the hypothesis that serotonin (5-hydroxytryptamine [5-HT]) exerts stimulatory and inhibitory effects on hepatic glucose disposal. Ligands of diverse 5-HT receptors were used to...

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Detalles Bibliográficos
Autores principales:	Tudhope, Susan J., Wang, Chung-Chi, Petrie, John L., Potts, Lloyd, Malcomson, Fiona, Kieswich, Julius, Yaqoob, Muhammad M., Arden, Catherine, Hampson, Laura J., Agius, Loranne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237670/ https://www.ncbi.nlm.nih.gov/pubmed/22106156 http://dx.doi.org/10.2337/db11-0870

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