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Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians

Features of melanocortin-4 receptor (MC4R) deficiency have been observed to be more pronounced in childhood. Longitudinal data from a population-based study were used to separate the phenotypic effects of MC4R deficiency during childhood and adulthood. The MC4R exon was sequenced in 6,760 individual...

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Detalles Bibliográficos
Autores principales:	Thearle, Marie S., Muller, Yunhua L., Hanson, Robert L., Mullins, Meghan, AbdusSamad, Maryam, Tran, John, Knowler, William C., Bogardus, Clifton, Krakoff, Jonathan, Baier, Leslie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237672/ https://www.ncbi.nlm.nih.gov/pubmed/22106157 http://dx.doi.org/10.2337/db11-0708

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