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Physicochemical and biological characterization of 1E10 Anti-Idiotype vaccine

BACKGROUND: 1E10 monoclonal antibody is a murine anti-idiotypic antibody that mimics N-glycolyl-GM3 gangliosides. This antibody has been tested as an anti-idiotypic cancer vaccine, adjuvated in Al(OH)(3), in several clinical trials for melanoma, breast, and lung cancer. During early clinical develop...

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Detalles Bibliográficos
Autores principales:	Machado, Yoan J, Rabasa, Yamilet, Montesinos, Raquel, Cremata, José, Besada, Vladimir, Fuentes, Dasha, Castillo, Adolfo, de la Luz, Kathya R, Vázquez, Ana M, Himly, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238287/ https://www.ncbi.nlm.nih.gov/pubmed/22108317 http://dx.doi.org/10.1186/1472-6750-11-112

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