Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis

BACKGROUND: Myelin/oligodendrocyte glycoprotein (MOG) is a putative autoantigen in multiple sclerosis (MS). Establishing the pathological relevance and validity of anti-MOG antibodies as biomarkers has yielded conflicting reports mainly due to different MOG isoforms used in different studies. Becaus...

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Detalles Bibliográficos
Autores principales: Menge, Til, Lalive, Patrice H, von Büdingen, H -Christian, Genain , Claude P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238300/
https://www.ncbi.nlm.nih.gov/pubmed/22093619
http://dx.doi.org/10.1186/1742-2094-8-161

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