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Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice

Preventing tissue-factor-(TF-) mediated systemic coagulopathy improves outcome in models of sepsis. Preventing TF-mediated pulmonary coagulopathy could attenuate ventilator-induced lung injury (VILI). We investigated the effect of relative TF deficiency on pulmonary coagulopathy and inflammation in...

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Detalles Bibliográficos
Autores principales:	Wolthuis, Esther K., Vlaar, Alexander P. J., Choi, Goda, Roelofs, Joris J. T. H., Levi, Marcel, Juffermans, Nicole P., Schultz, Marcus J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238356/ https://www.ncbi.nlm.nih.gov/pubmed/22195278 http://dx.doi.org/10.1155/2012/130410

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