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Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer
Alternative splicing of the IgIII loop of fibroblast growth factor receptors (FGFRs) 1–3 produces b- and c-variants of the receptors with distinctly different biological impact based on their distinct ligand-binding spectrum. Tissue-specific expression of these splice variants regulates interactions...
Autores principales: | Holzmann, Klaus, Grunt, Thomas, Heinzle, Christine, Sampl, Sandra, Steinhoff, Heinrich, Reichmann, Nicole, Kleiter, Miriam, Hauck, Marlene, Marian, Brigitte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238399/ https://www.ncbi.nlm.nih.gov/pubmed/22203889 http://dx.doi.org/10.1155/2012/950508 |
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