Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’

The title compound [systematic name: (1S,4S,5R,7S,8S,9R,10R,11S,13S,14S,16S,17R)-N-methyl-8,14-dihy­droxy-1,16-tri­meth­oxy-4-(meth­oxy­methyl­ene)aconitane], C(24)H(39)NO(5), was isolated from the roots of Aconitum carmichaelii Debx., which is known as ‘Chuanwu’ in Chinese traditional herbal medici...

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Autores principales: Lei, Jun, Luo, Ya-Jun, Bian, Qing-Quan, Wang, Xiong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238819/
https://www.ncbi.nlm.nih.gov/pubmed/22199672
http://dx.doi.org/10.1107/S1600536811044242
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author Lei, Jun
Luo, Ya-Jun
Bian, Qing-Quan
Wang, Xiong-Qing
author_facet Lei, Jun
Luo, Ya-Jun
Bian, Qing-Quan
Wang, Xiong-Qing
author_sort Lei, Jun
collection PubMed
description The title compound [systematic name: (1S,4S,5R,7S,8S,9R,10R,11S,13S,14S,16S,17R)-N-methyl-8,14-dihy­droxy-1,16-tri­meth­oxy-4-(meth­oxy­methyl­ene)aconitane], C(24)H(39)NO(5), was isolated from the roots of Aconitum carmichaelii Debx., which is known as ‘Chuanwu’ in Chinese traditional herbal medicine. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings, including a six-membered N-containing heterocyclic ring. Both five-membered rings adopt envelope conformations. The four six-membered adopt chair conformations. Two intra­molecular O—H⋯O hydrogen bonds occur.
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spelling pubmed-32388192011-12-23 Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’ Lei, Jun Luo, Ya-Jun Bian, Qing-Quan Wang, Xiong-Qing Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound [systematic name: (1S,4S,5R,7S,8S,9R,10R,11S,13S,14S,16S,17R)-N-methyl-8,14-dihy­droxy-1,16-tri­meth­oxy-4-(meth­oxy­methyl­ene)aconitane], C(24)H(39)NO(5), was isolated from the roots of Aconitum carmichaelii Debx., which is known as ‘Chuanwu’ in Chinese traditional herbal medicine. The mol­ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings, including a six-membered N-containing heterocyclic ring. Both five-membered rings adopt envelope conformations. The four six-membered adopt chair conformations. Two intra­molecular O—H⋯O hydrogen bonds occur. International Union of Crystallography 2011-11-02 /pmc/articles/PMC3238819/ /pubmed/22199672 http://dx.doi.org/10.1107/S1600536811044242 Text en © Lei et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Lei, Jun
Luo, Ya-Jun
Bian, Qing-Quan
Wang, Xiong-Qing
Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title_full Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title_fullStr Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title_full_unstemmed Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title_short Talatisamine, a C(19)-diterpenoid alkaloid from Chinese traditional herbal ‘Chuanwu’
title_sort talatisamine, a c(19)-diterpenoid alkaloid from chinese traditional herbal ‘chuanwu’
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238819/
https://www.ncbi.nlm.nih.gov/pubmed/22199672
http://dx.doi.org/10.1107/S1600536811044242
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