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7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione
In the title compound, C(29)H(20)F(3)NO(3)S, the thiazolidine ringadopts a half-chair conformation. The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps. The trifluoromethyl-substituted benzene ring forms dihedral angles of 62.37...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238947/ https://www.ncbi.nlm.nih.gov/pubmed/22199796 http://dx.doi.org/10.1107/S1600536811047118 |
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| author | Wei, Ang Chee Ali, Mohamed Ashraf Ismail, Rusli Quah, Ching Kheng Fun, Hoong-Kun |
| author_facet | Wei, Ang Chee Ali, Mohamed Ashraf Ismail, Rusli Quah, Ching Kheng Fun, Hoong-Kun |
| author_sort | Wei, Ang Chee |
| collection | PubMed |
| description | In the title compound, C(29)H(20)F(3)NO(3)S, the thiazolidine ringadopts a half-chair conformation. The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps. The trifluoromethyl-substituted benzene ring forms dihedral angles of 62.37 (14) and 87.40 (14)° with the benzene rings of the dihydro-1H-indene units. The two benzene rings form a dihedral angle of 36.94 (15)°. The molecular structure is stabilized by intramolecular C—H⋯O hydrogen bonds, which generate S(6) ring motifs. In the crystal, molecules are linked into inversion dimers by pairs of intermolecular C—H⋯O hydrogen bonds, generating R (2) (2)(10) ring motifs. |
| format | Online Article Text |
| id | pubmed-3238947 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-32389472011-12-23 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione Wei, Ang Chee Ali, Mohamed Ashraf Ismail, Rusli Quah, Ching Kheng Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(29)H(20)F(3)NO(3)S, the thiazolidine ringadopts a half-chair conformation. The pyrrolidine and two five-membered carbocyclic rings are in envelope conformations with the spiro C atoms at the flaps. The trifluoromethyl-substituted benzene ring forms dihedral angles of 62.37 (14) and 87.40 (14)° with the benzene rings of the dihydro-1H-indene units. The two benzene rings form a dihedral angle of 36.94 (15)°. The molecular structure is stabilized by intramolecular C—H⋯O hydrogen bonds, which generate S(6) ring motifs. In the crystal, molecules are linked into inversion dimers by pairs of intermolecular C—H⋯O hydrogen bonds, generating R (2) (2)(10) ring motifs. International Union of Crystallography 2011-11-12 /pmc/articles/PMC3238947/ /pubmed/22199796 http://dx.doi.org/10.1107/S1600536811047118 Text en © Wei et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Wei, Ang Chee Ali, Mohamed Ashraf Ismail, Rusli Quah, Ching Kheng Fun, Hoong-Kun 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title | 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title_full | 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title_fullStr | 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title_full_unstemmed | 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title_short | 7′-[4-(Trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| title_sort | 7′-[4-(trifluoromethyl)phenyl]-5′,6′,7′,7a’-tetrahydrodispiro[indan-2,5′-pyrrolo[1,2-c][1,3]thiazole-6′,2′′-indan]-1,3,1′′-trione |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238947/ https://www.ncbi.nlm.nih.gov/pubmed/22199796 http://dx.doi.org/10.1107/S1600536811047118 |
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