5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one

In the title compound, C(17)H(16)N(2)O(3), the seven-membered diazepine ring adopts a boat conformation with the hy­droxy-substituted C atom at the prow and fused benzene ring C atoms at the stern. The phenyl substituent occupies an equatorial position. The amino group of the ring system is a hydrog...

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Autores principales: Rida, Mohamed, Alsubari, Abdusalam, Essassi, El Mokhtar, Zouihri, Hafid, Ng, Seik Weng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238984/
https://www.ncbi.nlm.nih.gov/pubmed/22199833
http://dx.doi.org/10.1107/S1600536811047878
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author Rida, Mohamed
Alsubari, Abdusalam
Essassi, El Mokhtar
Zouihri, Hafid
Ng, Seik Weng
author_facet Rida, Mohamed
Alsubari, Abdusalam
Essassi, El Mokhtar
Zouihri, Hafid
Ng, Seik Weng
author_sort Rida, Mohamed
collection PubMed
description In the title compound, C(17)H(16)N(2)O(3), the seven-membered diazepine ring adopts a boat conformation with the hy­droxy-substituted C atom at the prow and fused benzene ring C atoms at the stern. The phenyl substituent occupies an equatorial position. The amino group of the ring system is a hydrogen-bond donor to the oxo O atom of an inversion-related mol­ecule, and the hy­droxy group is a hydrogen-bond donor to the acetyl O atom of another inversion-related mol­ecule. The two hydrogen bonds generate a ribbon motif parallel to [10[Image: see text]] in the crystal structure.
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spelling pubmed-32389842011-12-23 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one Rida, Mohamed Alsubari, Abdusalam Essassi, El Mokhtar Zouihri, Hafid Ng, Seik Weng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(17)H(16)N(2)O(3), the seven-membered diazepine ring adopts a boat conformation with the hy­droxy-substituted C atom at the prow and fused benzene ring C atoms at the stern. The phenyl substituent occupies an equatorial position. The amino group of the ring system is a hydrogen-bond donor to the oxo O atom of an inversion-related mol­ecule, and the hy­droxy group is a hydrogen-bond donor to the acetyl O atom of another inversion-related mol­ecule. The two hydrogen bonds generate a ribbon motif parallel to [10[Image: see text]] in the crystal structure. International Union of Crystallography 2011-11-16 /pmc/articles/PMC3238984/ /pubmed/22199833 http://dx.doi.org/10.1107/S1600536811047878 Text en © Rida et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Rida, Mohamed
Alsubari, Abdusalam
Essassi, El Mokhtar
Zouihri, Hafid
Ng, Seik Weng
5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title_full 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title_fullStr 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title_full_unstemmed 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title_short 5-Acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1H-1,5-benzodiazepin-2(3H)-one
title_sort 5-acetyl-3-hy­droxy-4-phenyl-4,5-dihydro-1h-1,5-benzodiazepin-2(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238984/
https://www.ncbi.nlm.nih.gov/pubmed/22199833
http://dx.doi.org/10.1107/S1600536811047878
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