N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide

In the title compound, C(16)H(20)FN(3)O(3)S, the pyrimidine and benzene rings are oriented at a dihedral angle of 38.8 (3)°. An intra­molecular C—H⋯O hydrogen bond occurs. The crystal structure is stabilized by O—H⋯N hydrogen bonds. In addition, C—H⋯O inter­actions are also present.

Detalles Bibliográficos
Autores principales: Xu, Hong, Sun, Hong-shun, Luo, Feng-mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239065/
https://www.ncbi.nlm.nih.gov/pubmed/22199913
http://dx.doi.org/10.1107/S1600536811049051
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author Xu, Hong
Sun, Hong-shun
Luo, Feng-mao
author_facet Xu, Hong
Sun, Hong-shun
Luo, Feng-mao
author_sort Xu, Hong
collection PubMed
description In the title compound, C(16)H(20)FN(3)O(3)S, the pyrimidine and benzene rings are oriented at a dihedral angle of 38.8 (3)°. An intra­molecular C—H⋯O hydrogen bond occurs. The crystal structure is stabilized by O—H⋯N hydrogen bonds. In addition, C—H⋯O inter­actions are also present.
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spelling pubmed-32390652011-12-23 N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide Xu, Hong Sun, Hong-shun Luo, Feng-mao Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(16)H(20)FN(3)O(3)S, the pyrimidine and benzene rings are oriented at a dihedral angle of 38.8 (3)°. An intra­molecular C—H⋯O hydrogen bond occurs. The crystal structure is stabilized by O—H⋯N hydrogen bonds. In addition, C—H⋯O inter­actions are also present. International Union of Crystallography 2011-11-25 /pmc/articles/PMC3239065/ /pubmed/22199913 http://dx.doi.org/10.1107/S1600536811049051 Text en © Xu et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Xu, Hong
Sun, Hong-shun
Luo, Feng-mao
N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title_full N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title_fullStr N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title_full_unstemmed N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title_short N-[4-(4-Fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-N-methyl­methane­sulfonamide
title_sort n-[4-(4-fluoro­phen­yl)-5-hy­droxy­methyl-6-isopropyl­pyrimidin-2-yl]-n-methyl­methane­sulfonamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239065/
https://www.ncbi.nlm.nih.gov/pubmed/22199913
http://dx.doi.org/10.1107/S1600536811049051
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AT sunhongshun n44fluorophenyl5hydroxymethyl6isopropylpyrimidin2ylnmethylmethanesulfonamide
AT luofengmao n44fluorophenyl5hydroxymethyl6isopropylpyrimidin2ylnmethylmethanesulfonamide

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