(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide

The title compound, C(38)H(36)N(2)O(2)S, has a heterocyclic ring that assumes a half-chair conformation. The phenyl rings of neighbouring mol­ecules align forming alternating chains parallel to [100] within the crystal packing. The absolute stereochemistry of the crystal was confirmed to be R,S at t...

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Detalles Bibliográficos
Autores principales: Naicker, Tricia, Govender, Thavendran, Kruger, Hendrick. G., Maguire, Glenn E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239074/
https://www.ncbi.nlm.nih.gov/pubmed/22199922
http://dx.doi.org/10.1107/S1600536811049324
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author Naicker, Tricia
Govender, Thavendran
Kruger, Hendrick. G.
Maguire, Glenn E. M.
author_facet Naicker, Tricia
Govender, Thavendran
Kruger, Hendrick. G.
Maguire, Glenn E. M.
author_sort Naicker, Tricia
collection PubMed
description The title compound, C(38)H(36)N(2)O(2)S, has a heterocyclic ring that assumes a half-chair conformation. The phenyl rings of neighbouring mol­ecules align forming alternating chains parallel to [100] within the crystal packing. The absolute stereochemistry of the crystal was confirmed to be R,S at the 1- and 3-positions, respectively, by proton NMR spectroscopy. A single intra­molecular N—H⋯N hydrogen bond is observed.
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spelling pubmed-32390742011-12-23 (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide Naicker, Tricia Govender, Thavendran Kruger, Hendrick. G. Maguire, Glenn E. M. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(38)H(36)N(2)O(2)S, has a heterocyclic ring that assumes a half-chair conformation. The phenyl rings of neighbouring mol­ecules align forming alternating chains parallel to [100] within the crystal packing. The absolute stereochemistry of the crystal was confirmed to be R,S at the 1- and 3-positions, respectively, by proton NMR spectroscopy. A single intra­molecular N—H⋯N hydrogen bond is observed. International Union of Crystallography 2011-11-25 /pmc/articles/PMC3239074/ /pubmed/22199922 http://dx.doi.org/10.1107/S1600536811049324 Text en © Naicker et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Naicker, Tricia
Govender, Thavendran
Kruger, Hendrick. G.
Maguire, Glenn E. M.
(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title_full (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title_fullStr (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title_full_unstemmed (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title_short (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
title_sort (1r,3s)-n-benzhydryl-2-benzyl-6,7-dimeth­oxy-1-phenyl-1,2,3,4-tetra­hydro­isoquinoline-3-carbothio­amide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239074/
https://www.ncbi.nlm.nih.gov/pubmed/22199922
http://dx.doi.org/10.1107/S1600536811049324
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