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Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate

In the title compound, C(24)H(22)N(2)O(6)S, a pyrimidine ring substituted with 4-hy­droxy-3-meth­oxy­phenyl is fused with a thia­zole ring. The 4-hy­droxy-3-meth­oxy­phenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat...

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Detalles Bibliográficos
Autores principales: Nagarajaiah, H., Begum, Noor Shahina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239076/
https://www.ncbi.nlm.nih.gov/pubmed/22199924
http://dx.doi.org/10.1107/S1600536811048987
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author Nagarajaiah, H.
Begum, Noor Shahina
author_facet Nagarajaiah, H.
Begum, Noor Shahina
author_sort Nagarajaiah, H.
collection PubMed
description In the title compound, C(24)H(22)N(2)O(6)S, a pyrimidine ring substituted with 4-hy­droxy-3-meth­oxy­phenyl is fused with a thia­zole ring. The 4-hy­droxy-3-meth­oxy­phenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat conformation. In the crystal, O—H⋯N inter­actions result in a chain running along the b axis. The carbonyl O atom bonded to the thia­zole ring is involved in two C—H⋯O hydrogen-bond inter­actions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these inter­actions have R (2) (2)(10) and R (1) (2)(6) motifs, respectively.
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spelling pubmed-32390762011-12-23 Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate Nagarajaiah, H. Begum, Noor Shahina Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(22)N(2)O(6)S, a pyrimidine ring substituted with 4-hy­droxy-3-meth­oxy­phenyl is fused with a thia­zole ring. The 4-hy­droxy-3-meth­oxy­phenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat conformation. In the crystal, O—H⋯N inter­actions result in a chain running along the b axis. The carbonyl O atom bonded to the thia­zole ring is involved in two C—H⋯O hydrogen-bond inter­actions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these inter­actions have R (2) (2)(10) and R (1) (2)(6) motifs, respectively. International Union of Crystallography 2011-11-25 /pmc/articles/PMC3239076/ /pubmed/22199924 http://dx.doi.org/10.1107/S1600536811048987 Text en © Nagarajaiah and Begum 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Nagarajaiah, H.
Begum, Noor Shahina
Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title_full Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title_fullStr Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title_full_unstemmed Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title_short Methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5H-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
title_sort methyl 5-(4-hy­droxy-3-meth­oxy­phen­yl)-2-(4-meth­oxy­benzyl­idene)-7-methyl-3-oxo-2,3-dihydro-5h-thia­zolo[3,2-a]pyrimidine-6-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239076/
https://www.ncbi.nlm.nih.gov/pubmed/22199924
http://dx.doi.org/10.1107/S1600536811048987
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AT begumnoorshahina methyl54hydroxy3methoxyphenyl24methoxybenzylidene7methyl3oxo23dihydro5hthiazolo32apyrimidine6carboxylate