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3-[4-(10H-Indolo[3,2-b]quinolin-11-yl)piperazin-1-yl]propan-1-ol

In the title compound, C(22)H(24)N(4)O, the aromatic moiety is essentially planar (r.m.s. deviation of a least-squares plane fitted through all non-H atoms = 0.0386 Å) and is rotated by 89.98 (4)° from the piperazine ring, which adopts the expected chair conformation. The propanol chain is not fully...

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Detalles Bibliográficos
Autores principales: Nichol, Gary S., Boddupally, Peda V. L., De, Biswanath, Hurley, Laurence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239093/
https://www.ncbi.nlm.nih.gov/pubmed/22199941
http://dx.doi.org/10.1107/S1600536811050215
Descripción
Sumario:In the title compound, C(22)H(24)N(4)O, the aromatic moiety is essentially planar (r.m.s. deviation of a least-squares plane fitted through all non-H atoms = 0.0386 Å) and is rotated by 89.98 (4)° from the piperazine ring, which adopts the expected chair conformation. The propanol chain is not fully extended away from the piperazine ring. In the crystal, there are two unique hydrogen-bonding inter­actions. One is an O—H⋯N inter­action which, together with an inversion-related symmetry equivalent, forms a ring motif. The second is an N—H⋯N inter­action which links adjacent mol­ecules by means of a chain motif which propagates in the c-axis direction. Overall, a two-dimensional hydrogen-bonded structure is formed.