4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile

The title compound, C(22)H(20)N(2)O(2), was synthesized via a multicomponent reaction using naphthalen-2-ol, morpholine and 4-formyl­benzonitrile. The dihedral angle between the naphthalene ring system and the benzene ring is 81.25 (10)°. The morpholine ring adopts a chair conformation. The mol­ecul...

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Detalles Bibliográficos
Autores principales: Chen, Xin-Yuan, Zhao, Min-Min, Qian, Xu, Hou, Shao-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239108/
https://www.ncbi.nlm.nih.gov/pubmed/22199956
http://dx.doi.org/10.1107/S160053681104997X
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author Chen, Xin-Yuan
Zhao, Min-Min
Qian, Xu
Hou, Shao-Gang
author_facet Chen, Xin-Yuan
Zhao, Min-Min
Qian, Xu
Hou, Shao-Gang
author_sort Chen, Xin-Yuan
collection PubMed
description The title compound, C(22)H(20)N(2)O(2), was synthesized via a multicomponent reaction using naphthalen-2-ol, morpholine and 4-formyl­benzonitrile. The dihedral angle between the naphthalene ring system and the benzene ring is 81.25 (10)°. The morpholine ring adopts a chair conformation. The mol­ecular conformation is stabilized by intra­molecular O—H⋯N and C—H⋯O hydrogen bonds. In the crystal, inter­molecular C—H⋯N hydrogen bonds link mol­ecules into helical chains running parallel to the c axis.
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spelling pubmed-32391082011-12-23 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile Chen, Xin-Yuan Zhao, Min-Min Qian, Xu Hou, Shao-Gang Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(22)H(20)N(2)O(2), was synthesized via a multicomponent reaction using naphthalen-2-ol, morpholine and 4-formyl­benzonitrile. The dihedral angle between the naphthalene ring system and the benzene ring is 81.25 (10)°. The morpholine ring adopts a chair conformation. The mol­ecular conformation is stabilized by intra­molecular O—H⋯N and C—H⋯O hydrogen bonds. In the crystal, inter­molecular C—H⋯N hydrogen bonds link mol­ecules into helical chains running parallel to the c axis. International Union of Crystallography 2011-11-30 /pmc/articles/PMC3239108/ /pubmed/22199956 http://dx.doi.org/10.1107/S160053681104997X Text en © Chen et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Chen, Xin-Yuan
Zhao, Min-Min
Qian, Xu
Hou, Shao-Gang
4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title_full 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title_fullStr 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title_full_unstemmed 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title_short 4-[(2-Hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
title_sort 4-[(2-hy­droxy­naphthalen-1-yl)(morpholin-4-yl)meth­yl]benzonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239108/
https://www.ncbi.nlm.nih.gov/pubmed/22199956
http://dx.doi.org/10.1107/S160053681104997X
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AT houshaogang 42hydroxynaphthalen1ylmorpholin4ylmethylbenzonitrile

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