Cargando…
1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid
In the title compound, C(17)H(20)N(2)O(3), the methoxyphenyl unit is disordered over two sets of sites in a 0.715 (4):0.285 (4) ratio. The pyrazole ring forms dihedral angles of 55.88 (16) and 72.6 (4)° with the benzene rings of its major and minor components, respectively. The cyclohexane ring a...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239134/ https://www.ncbi.nlm.nih.gov/pubmed/22199982 http://dx.doi.org/10.1107/S1600536811050872 |
| _version_ | 1782219132422324224 |
|---|---|
| author | Fun, Hoong-Kun Quah, Ching Kheng Chandrakantha, B. Isloor, A. M. Shetty, Prakash |
| author_facet | Fun, Hoong-Kun Quah, Ching Kheng Chandrakantha, B. Isloor, A. M. Shetty, Prakash |
| author_sort | Fun, Hoong-Kun |
| collection | PubMed |
| description | In the title compound, C(17)H(20)N(2)O(3), the methoxyphenyl unit is disordered over two sets of sites in a 0.715 (4):0.285 (4) ratio. The pyrazole ring forms dihedral angles of 55.88 (16) and 72.6 (4)° with the benzene rings of its major and minor components, respectively. The cyclohexane ring adopts a chair conformation and its C—N bond is in an equatorial orientation. In the crystal, molecules are linked into inversion dimers by pairs of O—H⋯O hydrogen bonds, generating R (2) (2)(8) loops. |
| format | Online Article Text |
| id | pubmed-3239134 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-32391342011-12-23 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid Fun, Hoong-Kun Quah, Ching Kheng Chandrakantha, B. Isloor, A. M. Shetty, Prakash Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(17)H(20)N(2)O(3), the methoxyphenyl unit is disordered over two sets of sites in a 0.715 (4):0.285 (4) ratio. The pyrazole ring forms dihedral angles of 55.88 (16) and 72.6 (4)° with the benzene rings of its major and minor components, respectively. The cyclohexane ring adopts a chair conformation and its C—N bond is in an equatorial orientation. In the crystal, molecules are linked into inversion dimers by pairs of O—H⋯O hydrogen bonds, generating R (2) (2)(8) loops. International Union of Crystallography 2011-11-30 /pmc/articles/PMC3239134/ /pubmed/22199982 http://dx.doi.org/10.1107/S1600536811050872 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Fun, Hoong-Kun Quah, Ching Kheng Chandrakantha, B. Isloor, A. M. Shetty, Prakash 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title | 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title_full | 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title_fullStr | 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title_full_unstemmed | 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title_short | 1-Cyclohexyl-5-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid |
| title_sort | 1-cyclohexyl-5-(4-methoxyphenyl)-1h-pyrazole-4-carboxylic acid |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239134/ https://www.ncbi.nlm.nih.gov/pubmed/22199982 http://dx.doi.org/10.1107/S1600536811050872 |
| work_keys_str_mv | AT funhoongkun 1cyclohexyl54methoxyphenyl1hpyrazole4carboxylicacid AT quahchingkheng 1cyclohexyl54methoxyphenyl1hpyrazole4carboxylicacid AT chandrakanthab 1cyclohexyl54methoxyphenyl1hpyrazole4carboxylicacid AT islooram 1cyclohexyl54methoxyphenyl1hpyrazole4carboxylicacid AT shettyprakash 1cyclohexyl54methoxyphenyl1hpyrazole4carboxylicacid |