Influence of ground-state structure and Mg(2+) binding on folding kinetics of the guanine-sensing riboswitch aptamer domain

Riboswitch RNAs fold into complex tertiary structures upon binding to their cognate ligand. Ligand recognition is accomplished by key residues in the binding pocket. In addition, it often crucially depends on the stability of peripheral structural elements. The ligand-bound complex of the guanine-se...

Descripción completa

Detalles Bibliográficos
Autores principales: Buck, Janina, Wacker, Anna, Warkentin, Eberhart, Wöhnert, Jens, Wirmer-Bartoschek, Julia, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239184/
https://www.ncbi.nlm.nih.gov/pubmed/21890900
http://dx.doi.org/10.1093/nar/gkr664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239184/
https://www.ncbi.nlm.nih.gov/pubmed/21890900
http://dx.doi.org/10.1093/nar/gkr664

Ejemplares similares