Improved accuracy of supervised CRM discovery with interpolated Markov models and cross-species comparison

Despite recent advances in experimental approaches for identifying transcriptional cis-regulatory modules (CRMs, ‘enhancers’), direct empirical discovery of CRMs for all genes in all cell types and environmental conditions is likely to remain an elusive goal. Effective methods for computational CRM...

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Detalles Bibliográficos
Autores principales: Kazemian, Majid, Zhu, Qiyun, Halfon, Marc S., Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239187/
https://www.ncbi.nlm.nih.gov/pubmed/21821659
http://dx.doi.org/10.1093/nar/gkr621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239187/
https://www.ncbi.nlm.nih.gov/pubmed/21821659
http://dx.doi.org/10.1093/nar/gkr621

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