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Integration of sequence-similarity and functional association information can overcome intrinsic problems in orthology mapping across bacterial genomes
Existing methods for orthologous gene mapping suffer from two general problems: (i) they are computationally too slow and their results are difficult to interpret for automated large-scale applications when based on phylogenetic analyses; or (ii) they are too prone to making mistakes in dealing with...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239196/ https://www.ncbi.nlm.nih.gov/pubmed/21965536 http://dx.doi.org/10.1093/nar/gkr766 |