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Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease

BACKGROUND: Intravenous immunoglobulin (IVIg) treatment results in an effective response from patients with acute-phase Kawasaki disease (KD), but 16.5% of them remain nonresponsive to IVIg. To address this therapeutic challenge, we tried a new therapeutic drug, mizoribine (MZR), in a mouse model of...

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Detalles Bibliográficos
Autores principales:	Takahashi, Kei, Oharaseki, Toshiaki, Nagao, Tomokazu, Yokouchi, Yuki, Yamada, Hitomi, Nagi-Miura, Noriko, Ohno, Naohito, Saji, Tsutomu, Okazaki, Tomio, Suzuki, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239324/ https://www.ncbi.nlm.nih.gov/pubmed/21958311 http://dx.doi.org/10.1186/1546-0096-9-30

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