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Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

INTRODUCTION: To examine the effects of tumour necrosis factor (TNF) blocking therapy on the levels of early mitochondrial genome alterations and oxidative stress. METHODS: Eighteen inflammatory arthritis patients underwent synovial tissue oxygen (tpO(2)) measurements and clinical assessment of dise...

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Detalles Bibliográficos
Autores principales:	Biniecka, Monika, Kennedy, Aisling, Ng, Chin T, Chang, Ting C, Balogh, Emese, Fox, Edward, Veale, Douglas J, Fearon, Ursula, O'Sullivan, Jacintha N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239359/ https://www.ncbi.nlm.nih.gov/pubmed/21787418 http://dx.doi.org/10.1186/ar3424

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