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Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy
Blocking IL-1 in patients with knee osteoarthritis is an attractive strategy. Cohen and colleagues report a randomised, placebo-controlled, multiple-dose trial using a monoclonal antibody blocking IL-1 type 1 receptor. They failed to show any positive results in terms of evolution of pain for up to...
Autores principales: | Chevalier, Xavier, Conrozier, Thierry, Richette, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239369/ https://www.ncbi.nlm.nih.gov/pubmed/21888686 http://dx.doi.org/10.1186/ar3436 |
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