Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand

INTRODUCTION: Cathepsin K is a recently discovered cysteine protease which cleaves the triple helical domains of type I to II collagen. It has been shown to be up-regulated in synovial tissue from osteoarthritic and rheumatoid patients, and is a component in normal and nonarthritic cartilage, where...

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Detalles Bibliográficos
Autores principales: Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239383/
https://www.ncbi.nlm.nih.gov/pubmed/21880134
http://dx.doi.org/10.1186/ar3454

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