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Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition
BACKGROUND: The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex metabolomic data. At present, the...
Autores principales: | Xiao, Xiaolin, Dawson, Neil, MacIntyre, Lynsey, Morris, Brian J, Pratt, Judith A, Watson, David G, Higham, Desmond J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239845/ https://www.ncbi.nlm.nih.gov/pubmed/21575198 http://dx.doi.org/10.1186/1752-0509-5-72 |
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