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Tissue engineering: chondrocytes and cartilage

CHAPTER SUMMARY: Tissue engineering offers new strategies for developing treatments for the repair and regeneration of damaged and diseased tissues. These treatments, using living cells, will exploit new developments in understanding the principles in cell biology that control and direct cell functi...

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Detalles Bibliográficos
Autores principales: Hardingham, Tim, Tew, Simon, Murdoch, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240137/
https://www.ncbi.nlm.nih.gov/pubmed/12110124
http://dx.doi.org/10.1186/ar561
Descripción
Sumario:CHAPTER SUMMARY: Tissue engineering offers new strategies for developing treatments for the repair and regeneration of damaged and diseased tissues. These treatments, using living cells, will exploit new developments in understanding the principles in cell biology that control and direct cell function. Arthritic diseases that affect so many people and have a major impact on the quality of life provide an important target for tissue engineering. Initial approaches are in cartilage repair; in our own programme we are elucidating the signals required by chondrocytes to promote new matrix assembly. These principles will extend to other tissues of the musculoskeletal system, including the repair of bone, ligament and tendon.