Cargando…

The paradigm of IL-6: from basic science to medicine

CHAPTER SUMMARY: IL-6 is a pleiotropic cytokine with a wide range of biological activities in immune regulation, hematopoiesis, inflammation, and oncogenesis. Its activities are shared by IL-6-related cytokines such as leukemia inhibitory factor and oncostatin M. The pleiotropy and redundancy of IL-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naka, Tetsuji, Nishimoto, Norihiro, Kishimoto, Tadamitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240141/ https://www.ncbi.nlm.nih.gov/pubmed/12110143 http://dx.doi.org/10.1186/ar565

Ejemplares similares

Joint disease caused by defective gp130-mediated STAT signaling
por: Naka, Tetsuji, et al.
Publicado: (2002)

The Two-Faced Cytokine IL-6 in Host Defense and Diseases
por: Narazaki, Masashi, et al.
Publicado: (2018)

Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
por: Nishimoto, Norihiro, et al.
Publicado: (2008)

Differential Effects of IL-2 and IL-6 on the Development of Three Distinct Precursor T-Cell Populations in the Thymus
por: Nakano, Naoko, et al.
Publicado: (1990)

Interleukin-6: discovery of a pleiotropic cytokine
por: Kishimoto, Tadamitsu
Publicado: (2006)

Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases
por: Tanaka, Toshio, et al.
Publicado: (2012)

Impact of Basic Sciences on Medicine
por: Levitin, Howard
Publicado: (1967)

Translating IL-6 biology into effective treatments
por: Choy, Ernest H., et al.
Publicado: (2020)

Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms
por: Kang, Sujin, et al.
Publicado: (2021)

Pathogenic roles of IL-6 and IL-6 blocking therapy on rheumatoid arthritis
por: Yoshizaki, K, et al.
Publicado: (2003)

The immunobiology of humanized Anti-IL6 receptor antibody: From basic research to breakthrough medicine
por: Ohsugi, Yoshiyuki
Publicado: (2019)

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis
por: Mihara, Masahiko, et al.
Publicado: (2011)

Historical overview of the interleukin-6 family cytokine
por: Kang, Sujin, et al.
Publicado: (2020)

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses
por: Kimura, Akihiro, et al.
Publicado: (2009)

Alzheimer’s disease: from basic science to precision medicine approach
por: Forloni, Gianluigi
Publicado: (2020)

Rotator cuff disorders: Basic science and clinical medicine
por: Alokaily, Fahdah
Publicado: (2014)

Basic Facts for Basic Science
por: Oppenheim, Michael I.
Publicado: (1991)

ABSTRACTS OF SOVIET MEDICINE, PART A—BASIC MEDICAL SCIENCES
Publicado: (1957)

The in vivo Anti‐tumor Effect of Human Recombinant Interleukin‐6
por: Kitahara, Misa, et al.
Publicado: (1990)

Correction: Historical overview of the interleukin-6 family cytokine
por: Kang, Sujin, et al.
Publicado: (2020)

Cancer Organoids in Basic Science and Translational Medicine
por: Memeo, Lorenzo, et al.
Publicado: (2021)

Review of "bioinformatics basics: applications in biological science and medicine" by Buehler & Rashidi
por: Culhane, Aedín
Publicado: (2006)

Signal Transducer and Activator of Transcription (Stat)-Induced Stat Inhibitor 1 (Ssi-1)/Suppressor of Cytokine Signaling 1 (Socs1) Inhibits Insulin Signal Transduction Pathway through Modulating Insulin Receptor Substrate 1 (Irs-1) Phosphorylation
por: Kawazoe, Yoshinori, et al.
Publicado: (2001)

The emerging role of Arid5a in cancer: A new target for tumors
por: Nyati, Kishan Kumar, et al.
Publicado: (2022)

The Paradigm Change of IL-33 in Vascular Biology
por: Demyanets, Svitlana, et al.
Publicado: (2021)

Traditional Chinese Medicine in Treating IgA Nephropathy: From Basic Science to Clinical Research
por: Wang, Xin-hui, et al.
Publicado: (2021)

Anti-IL-6 Receptor Antibody Causes Less Promotion of Tuberculosis Infection than Anti-TNF-α Antibody in Mice
por: Okada, Masaji, et al.
Publicado: (2011)

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome
por: Kang, Sujin, et al.
Publicado: (2020)

Early administration of IL-6RA does not prevent radiation-induced lung injury in mice
por: Ogata, Toshiyuki, et al.
Publicado: (2010)

Basic science of nuclear medicine: the bare bone essentials
por: Lee, Kai H
Publicado: (2015)

An integrative paradigm to impart quality to correlative science
por: Kalos, Michael
Publicado: (2010)

Acoustic neuromodulation from a basic science prospective
por: Sassaroli, Elisabetta, et al.
Publicado: (2016)

Intravenous Irons: From Basic Science to Clinical Practice
por: Bhandari, Sunil, et al.
Publicado: (2018)

Minor Intron Splicing from Basic Science to Disease
por: El Marabti, Ettaib, et al.
Publicado: (2021)

Basic Sciences for Obstetrics and Gynaecology
por: McClure, Neil
Publicado: (1995)

TOXICOLOGY—THE BASIC SCIENCE OF POISONS
Publicado: (1976)

Translational research in Uganda: linking basic science to bedside medicine in a resource limited setting
por: Kwizera, Richard, et al.
Publicado: (2021)

Role of Basic Science in the Development of New Medicines: Examples from the Eicosanoid Field
por: Samuelsson, Bengt
Publicado: (2012)

Traditional Chinese Medicine in Treating Influenza: From Basic Science to Clinical Applications
por: Xiong, Yibai, et al.
Publicado: (2020)

The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
por: Shima, Yoshihito, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_s55jvau9u45od53gl6fkj16bqr