Cargando…

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

Caenorhabditis elegans ftn-1 and ftn-2, which encode the iron-storage protein ferritin, are transcriptionally inhibited during iron deficiency in intestine. Intestinal specific transcription is dependent on binding of ELT-2 to GATA binding sites in an iron-dependent enhancer (IDE) located in ftn-1 a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romney, Steven Joshua, Newman, Ben S., Thacker, Colin, Leibold, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240588/ https://www.ncbi.nlm.nih.gov/pubmed/22194696 http://dx.doi.org/10.1371/journal.pgen.1002394

Ejemplares similares

Mechanisms of iron metabolism in Caenorhabditis elegans
por: Anderson, Cole P., et al.
Publicado: (2014)

NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling
por: Rajan, Malini, et al.
Publicado: (2019)

Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans
por: Ackerman, Daniel, et al.
Publicado: (2012)

Iron Acquisition of Urinary Tract Infection Escherichia coli Involves Pathogenicity in Caenorhabditis elegans
por: Hashimoto, Masayuki, et al.
Publicado: (2021)

Differential Roles of Iron Storage Proteins in Maintaining the Iron Homeostasis in Mycobacterium tuberculosis
por: Khare, Garima, et al.
Publicado: (2017)

The Adaptive Mechanism of Plants to Iron Deficiency via Iron Uptake, Transport, and Homeostasis
por: Zhang, Xinxin, et al.
Publicado: (2019)

Silicon reduces the iron uptake in rice and induces iron homeostasis related genes
por: Becker, Martin, et al.
Publicado: (2020)

Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans
por: James, Simon A., et al.
Publicado: (2015)

Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans
por: Jenkins, Nicole L, et al.
Publicado: (2020)

The Regulator OmpR in Yersinia enterocolitica Participates in Iron Homeostasis by Modulating Fur Level and Affecting the Expression of Genes Involved in Iron Uptake
por: Jaworska, Karolina, et al.
Publicado: (2021)

A Cascade of Iron-Containing Proteins Governs the Genetic Iron Starvation Response to Promote Iron Uptake and Inhibit Iron Storage in Fission Yeast
por: Encinar del Dedo, Javier, et al.
Publicado: (2015)

Iron overload and neurodegenerative diseases: What can we learn from Caenorhabditis elegans?
por: Martins, Airton C, et al.
Publicado: (2022)

Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons
por: Pekec, Tina, et al.
Publicado: (2022)

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans
por: Feng, Dingxia, et al.
Publicado: (2021)

Caenorhabditis elegans HIF-1 Is Broadly Required for Survival in Hydrogen Sulfide
por: Topalidou, Irini, et al.
Publicado: (2017)

CUP-1 Is a Novel Protein Involved in Dietary Cholesterol Uptake in Caenorhabditis elegans
por: Valdes, Victor J., et al.
Publicado: (2012)

The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance
por: Page, Antony P.
Publicado: (2018)

Toxicity-based toxicokinetic/toxicodynamic assessment of bioaccumulation and nanotoxicity of zerovalent iron nanoparticles in Caenorhabditis elegans
por: Yang, Ying-Fei, et al.
Publicado: (2017)

Bacterial Metabolites Produced Under Iron Limitation Kill Pinewood Nematode and Attract Caenorhabditis elegans
por: Proença, Diogo Neves, et al.
Publicado: (2019)

Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans
por: Frumkin, Anna, et al.
Publicado: (2014)

Retinal iron homeostasis in health and disease
por: Song, Delu, et al.
Publicado: (2013)

Involvement of the Iron Regulatory Protein from Eisenia andrei Earthworms in the Regulation of Cellular Iron Homeostasis
por: Procházková, Petra, et al.
Publicado: (2014)

An Iron Transporter Is Involved in Iron Homeostasis, Energy Metabolism, Oxidative Stress, and Metacyclogenesis in Trypanosoma cruzi
por: Dick, Claudia F., et al.
Publicado: (2022)

Correction: CUP-1 Is a Novel Protein Involved in Dietary Cholesterol Uptake in Caenorhabditis elegans
por: Valdes, Victor J., et al.
Publicado: (2012)

Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders
por: Asthana, Abhishek, et al.
Publicado: (2017)

Pyoverdine-Mediated Killing of Caenorhabditis elegans by Pseudomonas syringae MB03 and the Role of Iron in Its Pathogenicity
por: Bashir, Anum, et al.
Publicado: (2020)

Impact of Tuning the Surface Charge Distribution on Colloidal Iron Oxide Nanoparticle Toxicity Investigated in Caenorhabditis elegans
por: Amigoni, Loredana, et al.
Publicado: (2021)

Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans
por: Pan, Weimin, et al.
Publicado: (2022)

Cadmium alters whole animal ionome and promotes the re-distribution of iron in intestinal cells of Caenorhabditis elegans
por: Sharma, Anuj Kumar, et al.
Publicado: (2023)

The Porphyromonas gingivalis ferric uptake regulator orthologue does not regulate iron homeostasis
por: Butler, Catherine, et al.
Publicado: (2015)

Multilayered regulation of iron homeostasis in Arabidopsis
por: Spielmann, Julien, et al.
Publicado: (2023)

Brain Iron Homeostasis: A Focus on Microglial Iron
por: Nnah, Israel C., et al.
Publicado: (2018)

Iron–Sulfur Cluster Biogenesis and Iron Homeostasis in Cyanobacteria
por: Gao, Fudan
Publicado: (2020)

Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond
por: Dietz, Jonathan V., et al.
Publicado: (2021)

Lactoferrin: A Natural Glycoprotein Involved in Iron and Inflammatory Homeostasis
por: Rosa, Luigi, et al.
Publicado: (2017)

Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa
por: Wu, Jiaojiao, et al.
Publicado: (2011)

BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis
por: Vara‐Pérez, Mónica, et al.
Publicado: (2021)

HIF-1 and SKN-1 Coordinate the Transcriptional Response to Hydrogen Sulfide in Caenorhabditis elegans
por: Miller, Dana L., et al.
Publicado: (2011)

HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium
por: Romanelli-Credrez, Laura, et al.
Publicado: (2020)

The physiological functions of iron regulatory proteins in iron homeostasis - an update
por: Zhang, De-Liang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ujt1ojan2b88ig6ikc422v4etn