Translating Clinical Findings into Knowledge in Drug Safety Evaluation - Drug Induced Liver Injury Prediction System (DILIps)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be translated into the development of predictiv...

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Detalles Bibliográficos
Autores principales: Liu, Zhichao, Shi, Qiang, Ding, Don, Kelly, Reagan, Fang, Hong, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240589/
https://www.ncbi.nlm.nih.gov/pubmed/22194678
http://dx.doi.org/10.1371/journal.pcbi.1002310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240589/
https://www.ncbi.nlm.nih.gov/pubmed/22194678
http://dx.doi.org/10.1371/journal.pcbi.1002310

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