Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

The ribosome is critical for all aspects of cell growth due to its essential role in protein synthesis. Paradoxically, many Ribosomal proteins (Rps) act as tumour suppressors in Drosophila and vertebrates. To examine how reductions in Rps could lead to tissue overgrowth, we took advantage of the obs...

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Detalles Bibliográficos
Autores principales: Lin, Jane I., Mitchell, Naomi C., Kalcina, Marina, Tchoubrieva, Elly, Stewart, Mary J., Marygold, Steven J., Walker, Cherryl D., Thomas, George, Leevers, Sally J., Pearson, Richard B., Quinn, Leonie M., Hannan, Ross D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240600/
https://www.ncbi.nlm.nih.gov/pubmed/22194697
http://dx.doi.org/10.1371/journal.pgen.1002408

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