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Macrophage-Specific Chemokines Induced via Innate Immunity by Amino Acid Copolymers and Their Role in EAE
The random amino acid copolymer poly(Y,E,A,K)(n) (Copaxone®) is widely used in multiple sclerosis treatment and a second generation copolymer poly(Y,F,A,K)(n) with enhanced efficacy in experimental autoimmune encephalomyelitis in mice has been described. A major mechanism through which copolymers fu...
Autores principales: | Kovalchin, Joseph, Krieger, Jeffrey, Genova, Michelle, Kawamoto, Norio, Augustyniak, Michael, Collins, Kathryn, Bloom, Troy, Masci, Allyson, Hittinger, Tara, Dufour, Ingrid, Strominger, Jack L., Zanelli, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240613/ https://www.ncbi.nlm.nih.gov/pubmed/22194778 http://dx.doi.org/10.1371/journal.pone.0026274 |
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