Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

BACKGROUND: Inhibitor of apoptosis proteins (IAPs) belong to a pivotal antiapoptotic protein family that plays a crucial role in tumorigenesis, cancer progression, chemoresistance and poor patient-survival. X-linked inhibitor of apoptosis protein (XIAP) is a prominent member of IAPs attracting inten...

Descripción completa

Detalles Bibliográficos
Autores principales: Tse, Man Kit, Hui, Sin Kam, Yang, Yinhua, Yin, Si-Tao, Hu, Hong-Yu, Zou, Bing, Wong, Benjamin Chun Yu, Sze, Kong Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240630/
https://www.ncbi.nlm.nih.gov/pubmed/22194841
http://dx.doi.org/10.1371/journal.pone.0028511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240630/
https://www.ncbi.nlm.nih.gov/pubmed/22194841
http://dx.doi.org/10.1371/journal.pone.0028511

Ejemplares similares