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Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association

BACKGROUND: Inhibitor of apoptosis proteins (IAPs) belong to a pivotal antiapoptotic protein family that plays a crucial role in tumorigenesis, cancer progression, chemoresistance and poor patient-survival. X-linked inhibitor of apoptosis protein (XIAP) is a prominent member of IAPs attracting inten...

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Detalles Bibliográficos
Autores principales:	Tse, Man Kit, Hui, Sin Kam, Yang, Yinhua, Yin, Si-Tao, Hu, Hong-Yu, Zou, Bing, Wong, Benjamin Chun Yu, Sze, Kong Hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240630/ https://www.ncbi.nlm.nih.gov/pubmed/22194841 http://dx.doi.org/10.1371/journal.pone.0028511

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